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Replacement filler Product List

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Bond Elut SCX

Bond Elut SCX

Bond Elut SCX is a strong cation exchange resin with a very low pKa similar to PRS.

Bond Elut SCX is a strong cation exchange resin with a very low pKa similar to PRS. However, due to the presence of benzene rings on the SCX surface, it has a higher potential for hydrophobic interactions compared to PRS. When using the packing material as an ion exchange in an aqueous solvent matrix, it is necessary to take into account the hydrophobic nature of SCX. This duality is beneficial for compounds that exhibit both cationic and hydrophobic properties. The interactions resulting from this dual nature are superior to purifications that use only a single binding phase. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut PSA

Bond Elut PSA

Bond Elut PSA is similar to NH2.

Bond Elut PSA is similar to NH2. The anion exchange resin PSA (1.4 meq/g) offers a slightly higher ion exchange capacity compared to NH2 (1.1 meq/g) due to its two amine groups, and the pKa of its primary and secondary amine groups is higher (10.1 and 10.9, respectively). Therefore, PSA is a slightly stronger anion exchanger than NH2. The PSA functional group has very good bidentate ligand properties, making PSA an excellent packing material for chelation. Higher carbon loading compared to NH2 packing materials promotes hydrophobicity and makes it a good choice for compounds with high polarity that are strongly retained by NH2 packing materials. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut PRS

Bond Elut PRS

Bond Elut PRS is a highly hydrophilic strong cation exchange that shows no notable hydrophobic interactions.

Bond Elut PRS is a highly hydrophilic strong cation exchange material, and there are no notable hydrophobic interactions observed. In non-polar solvents, it exhibits properties of hydrophilic interactions and hydrogen bonding. Due to the low pKa of PRS, cationic compounds must elute either by using a high ionic strength buffer or by suppressing the charge to isolate the cations. Therefore, PRS is effective for weak cations such as pyridine compounds. With relatively few hydrophobic secondary interactions, combined with its low capacity, PRS offers a unique set of selectivity features. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut DEA

Bond Elut DEA

The features of Bond Elut DEA and Bond Elut NH2 are similar in several respects.

The characteristics of Bond Elut DEA and Bond Elut NH2 are similar in several respects, and they are also somewhat akin to Bond Elut PSA. DEA has a slightly lower exchange capacity (1.0 meq/g) as an anion exchange packing material compared to NH2, and the addition of a carbon chain to the functional group has further increased its hydrophobicity. Even with the presence of the main functional group, DEA also functions as a packing material with moderate polarity due to the carbon chain. While DEA is somewhat more polar than C8, it is less polar than C2 or CN. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut CBA

Bond Elut CBA

Silica-based medium-polarity filler with carboxypropyl groups.

Bond Elut CBA is a silica-based medium-polarity packing material with carboxypropyl groups, which exhibits hydrophilic/hydrophobic interactions depending on the matrix and solvent environment. Its main characteristic lies in weak cation exchange. Due to its pKa value of 4.8, CBA does not require the extremely high alkaline environment that other cation exchange packing materials need for elution. At pH 4.8 and above, most of the functional groups carry a negative charge as cation exchange sites. Lowering the pH to 2.8 neutralizes CBA, allowing it to release and elute the compounds it has retained from the packing material. CBA is particularly suitable when dealing with very strong cationic compounds. Additionally, CBA broadens the selectivity range for counterions compared to other cation exchangers, increasing the options for elution buffers. *For more details, please refer to the PDF document or feel free to contact us.*

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